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Imine Resveratrol Analogues: Molecular Design, Nrf2 Activation and SAR Analysis

Resveratrol is a natural phenol with protective effects against cancer and inflammation-related diseases. Its mechanism of action involves the activation of nuclear factor E2 p45-related factor 2 (Nrf2), which plays a key role in regulation of genes driven by antioxidant response element (ARE). Insp...

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Detalles Bibliográficos
Autores principales: Li, Chang, Xu, Xiaofei, Wang, Xiu Jun, Pan, Yuanjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100753/
https://www.ncbi.nlm.nih.gov/pubmed/25028928
http://dx.doi.org/10.1371/journal.pone.0101455