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Imine Resveratrol Analogues: Molecular Design, Nrf2 Activation and SAR Analysis
Resveratrol is a natural phenol with protective effects against cancer and inflammation-related diseases. Its mechanism of action involves the activation of nuclear factor E2 p45-related factor 2 (Nrf2), which plays a key role in regulation of genes driven by antioxidant response element (ARE). Insp...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100753/ https://www.ncbi.nlm.nih.gov/pubmed/25028928 http://dx.doi.org/10.1371/journal.pone.0101455 |