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Dynamics of Linker Residues Modulate the Nucleic Acid Binding Properties of the HIV-1 Nucleocapsid Protein Zinc Fingers

The HIV-1 nucleocapsid protein (NC) is a small basic protein containing two zinc fingers (ZF) separated by a short linker. It is involved in several steps of the replication cycle and acts as a nucleic acid chaperone protein in facilitating nucleic acid strand transfers occurring during reverse tran...

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Detalles Bibliográficos
Autores principales: Zargarian, Loussiné, Tisné, Carine, Barraud, Pierre, Xu, Xiaoqian, Morellet, Nelly, René, Brigitte, Mély, Yves, Fossé, Philippe, Mauffret, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100767/
https://www.ncbi.nlm.nih.gov/pubmed/25029439
http://dx.doi.org/10.1371/journal.pone.0102150