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T-Cell Autophagy Deficiency Increases Mortality and Suppresses Immune Responses after Sepsis

BACKGROUND: Although the role of autophagy in sepsis has been characterized in several organs, its role in the adaptive immune system remains to be ascertained. This study aimed to investigate the role of autophagy in sepsis-induced T cell apoptosis and immunosuppression, using knockout mice with T...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Wen, Lo, Steven, Hsu, Chin, Hsieh, Chi-Hsun, Chang, Ya-Fang, Hou, Bao-Sheng, Kao, Ying-Hsien, Lin, Chih-Che, Yu, Ming-Lung, Yuan, Shyng-Shiou, Hsieh, Ya-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100769/
https://www.ncbi.nlm.nih.gov/pubmed/25029098
http://dx.doi.org/10.1371/journal.pone.0102066