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T-Cell Autophagy Deficiency Increases Mortality and Suppresses Immune Responses after Sepsis
BACKGROUND: Although the role of autophagy in sepsis has been characterized in several organs, its role in the adaptive immune system remains to be ascertained. This study aimed to investigate the role of autophagy in sepsis-induced T cell apoptosis and immunosuppression, using knockout mice with T...
Autores principales: | Lin, Chih-Wen, Lo, Steven, Hsu, Chin, Hsieh, Chi-Hsun, Chang, Ya-Fang, Hou, Bao-Sheng, Kao, Ying-Hsien, Lin, Chih-Che, Yu, Ming-Lung, Yuan, Shyng-Shiou, Hsieh, Ya-Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100769/ https://www.ncbi.nlm.nih.gov/pubmed/25029098 http://dx.doi.org/10.1371/journal.pone.0102066 |
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