Mechanistic Studies of Protein Arginine Deiminase 2: Evidence for a Substrate-Assisted Mechanism

[Image: see text] Citrullination, which is catalyzed by protein arginine deiminases (PADs 1–4 and 6), is a post-translational modification (PTM) that effectively neutralizes the positive charge of a guanidinium group by its replacement with a neutral urea. Given the sequence similarity of PAD2 acros...

Descripción completa

Detalles Bibliográficos
Autores principales: Dreyton, Christina J., Knuckley, Bryan, Jones, Justin E., Lewallen, Daniel M., Thompson, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100781/
https://www.ncbi.nlm.nih.gov/pubmed/24989433
http://dx.doi.org/10.1021/bi500554b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100781/
https://www.ncbi.nlm.nih.gov/pubmed/24989433
http://dx.doi.org/10.1021/bi500554b

Ejemplares similares