Transmission from centenarians to their offspring of mtDNA heteroplasmy revealed by ultra-deep sequencing

The role that mtDNA heteroplasmy plays in healthy aging, familial longevity and the heritability patterns of low levels heteroplasmy in the elderly are largely unknown. We analyzed the low levels of mtDNA heteroplasmy in blood in a cohort of centenarians, their offspring and a group of offspring of...

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Detalles Bibliográficos
Autores principales: Giuliani, Cristina, Barbieri, Chiara, Li, Mingkun, Bucci, Laura, Monti, Daniela, Passarino, Giuseppe, Luiselli, Donata, Franceschi, Claudio, Stoneking, Mark, Garagnani, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100808/
https://www.ncbi.nlm.nih.gov/pubmed/25013208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100808/
https://www.ncbi.nlm.nih.gov/pubmed/25013208

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