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Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway

Stiffening of large arteries is increasingly used as an independent predictor of risk and therapeutic outcome for small artery dysfunction in many diseases including pulmonary hypertension. The molecular mechanisms mediating downstream vascular cell responses to large artery stiffening remain unclea...

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Detalles Bibliográficos
Autores principales: Tan, Yan, Tseng, Pi-Ou, Wang, Daren, Zhang, Hui, Hunter, Kendall, Hertzberg, Jean, Stenmark, Kurt R., Tan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100881/
https://www.ncbi.nlm.nih.gov/pubmed/25029271
http://dx.doi.org/10.1371/journal.pone.0102195