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Identification of Drug Combinations Containing Imatinib for Treatment of BCR-ABL+ Leukemias

The BCR-ABL translocation is found in chronic myeloid leukemia (CML) and in Ph+ acute lymphoblastic leukemia (ALL) patients. Although imatinib and its analogues have been used as front-line therapy to target this mutation and control the disease for over a decade, resistance to the therapy is still...

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Detalles Bibliográficos
Autores principales: Kang, Yunyi, Hodges, Andrew, Ong, Edison, Roberts, William, Piermarocchi, Carlo, Paternostro, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100887/
https://www.ncbi.nlm.nih.gov/pubmed/25029499
http://dx.doi.org/10.1371/journal.pone.0102221