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Identification of Drug Combinations Containing Imatinib for Treatment of BCR-ABL+ Leukemias
The BCR-ABL translocation is found in chronic myeloid leukemia (CML) and in Ph+ acute lymphoblastic leukemia (ALL) patients. Although imatinib and its analogues have been used as front-line therapy to target this mutation and control the disease for over a decade, resistance to the therapy is still...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100887/ https://www.ncbi.nlm.nih.gov/pubmed/25029499 http://dx.doi.org/10.1371/journal.pone.0102221 |