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Diesterified Derivatives of 5-Iodo-2′-Deoxyuridine as Cerebral Tumor Tracers

With the aim to develop beneficial tracers for cerebral tumors, we tested two novel 5-iodo-2′-deoxyuridine (IUdR) derivatives, diesterified at the deoxyribose residue. The substances were designed to enhance the uptake into brain tumor tissue and to prolong the availability in the organism. We synth...

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Detalles Bibliográficos
Autores principales: Rösler, Thomas W., Matusch, Andreas, Librizzi, Damiano, Arias-Carrión, Oscar, Freundlieb, Nils, Hoeffken, Helmut, Oertel, Wolfgang H., Depboylu, Candan, Höglinger, Günter U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100890/
https://www.ncbi.nlm.nih.gov/pubmed/25028935
http://dx.doi.org/10.1371/journal.pone.0102397