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Cytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of CD5(+)CD19(+) B cells in the peripheral blood, and in primary and secondary lymphoid organs. A major complication associated with CLL is severe recurrent infections, which are often fatal. Vulnerability to infection is due to...

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Detalles Bibliográficos
Autores principales: Saulep-Easton, Damien, Vincent, Fabien B., Le Page, Melanie, Wei, Andrew, Ting, Stephen B., Croce, Carlo M., Tam, Constantine, Mackay, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100939/
https://www.ncbi.nlm.nih.gov/pubmed/24721775
http://dx.doi.org/10.1038/leu.2014.105