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Vemurafenib and panitumumab combination tailored therapy in BRAF-mutated metastatic colorectal cancer: A case report

As the knowledge on cancer genetic alterations progresses, it fosters the need for more personalized therapeutic intervention in modern cancer management. Recently, mutations in KRAS, BRAF, and PIK3CA genes have emerged as important mechanisms of resistance to EGFR-targeted therapy in metastatic col...

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Detalles Bibliográficos
Autores principales: Capalbo, Carlo, Marchetti, Paolo, Coppa, Anna, Calogero, Antonella, Anastasi, Emanuela, Buffone, Amelia, Belardinilli, Francesca, Gulino, Matteo, Frati, Paola, Catalano, Carlo, Cortesi, Enrico, Giannini, Giuseppe, Gulino, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100983/
https://www.ncbi.nlm.nih.gov/pubmed/24755613
http://dx.doi.org/10.4161/cbt.28878