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Combined PTEN Mutation and Protein Expression Associate with Overall and Disease-Free Survival of Glioblastoma Patients()()

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor commonly inactivated in glioblastoma multiforme (GBM), but the prognostic significance of PTEN remains controversial. Here, we demon- strate significant prognostic value of combined PTEN mutation and expression for...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Li, Zhaoli, Wang, Jilin, Chen, Haoyan, Fang, Jing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101389/
https://www.ncbi.nlm.nih.gov/pubmed/24721394
http://dx.doi.org/10.1016/j.tranon.2014.02.004