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Effects of the Chemokine Receptor 5 (CCR5)-Delta32 Mutation on Hepatitis C Virus-Specific Immune Responses and Liver Tissue Pathology in HCV Infected Patients

BACKGROUND: The specific antiviral T cells provide CC chemokine receptor 5 (CCR5) for the immune response during the hepatitis C virus (HCV) infection. Heterogenous and/or homozygous 32 base pair deletion in CCR5 gene (CCR5Δ32 bpdel) leads to reduced protein expression. OBJECTIVES: In the current ca...

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Detalles Bibliográficos
Autores principales: Yilmaz, Abdulkerim, Alagozlu, Hakan, Ozdemir, Ozturk, Arici, Sema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101423/
https://www.ncbi.nlm.nih.gov/pubmed/25067937
http://dx.doi.org/10.5812/hepatmon.11283