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PA28αβ: The Enigmatic Magic Ring of the Proteasome?

PA28αβ is a γ-interferon-induced 11S complex that associates with the ends of the 20S proteasome and stimulates in vitro breakdown of small peptide substrates, but not proteins or ubiquitin-conjugated proteins. In cells, PA28 also exists in larger complexes along with the 19S particle, which allows...

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Detalles Bibliográficos
Autor principal: Cascio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101498/
https://www.ncbi.nlm.nih.gov/pubmed/24970231
http://dx.doi.org/10.3390/biom4020566