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Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study

BACKGROUND: Genome-wide transcriptome profiling generated by microarray and RNA-Seq often provides deregulated genes or pathways applicable only to larger cohort. On the other hand, individualized interpretation of transcriptomes is increasely pursued to improve diagnosis, prognosis, and patient tre...

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Detalles Bibliográficos
Autores principales: Gardeux, Vincent, Arslan, Ahmet D, Achour, Ikbel, Ho, Tsui-Ting, Beck, William T, Lussier, Yves A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101571/
https://www.ncbi.nlm.nih.gov/pubmed/25079003
http://dx.doi.org/10.1186/1755-8794-7-S1-S1