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Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study
BACKGROUND: Genome-wide transcriptome profiling generated by microarray and RNA-Seq often provides deregulated genes or pathways applicable only to larger cohort. On the other hand, individualized interpretation of transcriptomes is increasely pursued to improve diagnosis, prognosis, and patient tre...
Autores principales: | Gardeux, Vincent, Arslan, Ahmet D, Achour, Ikbel, Ho, Tsui-Ting, Beck, William T, Lussier, Yves A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101571/ https://www.ncbi.nlm.nih.gov/pubmed/25079003 http://dx.doi.org/10.1186/1755-8794-7-S1-S1 |
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