Highly Efficient and Stereoselective Construction of Bispirooxindole Derivatives via a Three-Component 1,3-Dipolar Cycloaddition Reaction

A highly regio- and stereoselective synthesis of bispirooxindoles by 1,3-dipolar cycloaddition of in situ generated azomethine ylides from isatin and proline to different electron-deficient alkenes has been developed. The synthesis affords the desired bispiro scaffold compounds in excellent yields w...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Qin, Wang, De, Wei, Yin, Shi, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101724/
https://www.ncbi.nlm.nih.gov/pubmed/25050227
http://dx.doi.org/10.1002/open.201402003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101724/
https://www.ncbi.nlm.nih.gov/pubmed/25050227
http://dx.doi.org/10.1002/open.201402003

Ejemplares similares