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The Ca(2+)-activated Cl(−) channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesis
Since anoctamin 1 ANO1 (TMEM16A) was found to be a molecular component of Ca(2+)-activated Cl(−) channels, its role in tumorigenesis has gained attention at a fast pace. ANO1 overexpression frequently occurs in the cancer tissues along with 11q13 chromosome amplification. Poor prognosis of many type...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101736/ https://www.ncbi.nlm.nih.gov/pubmed/24639373 http://dx.doi.org/10.1002/cam4.232 |