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The Ca(2+)-activated Cl(−) channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesis

Since anoctamin 1 ANO1 (TMEM16A) was found to be a molecular component of Ca(2+)-activated Cl(−) channels, its role in tumorigenesis has gained attention at a fast pace. ANO1 overexpression frequently occurs in the cancer tissues along with 11q13 chromosome amplification. Poor prognosis of many type...

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Detalles Bibliográficos
Autores principales:	Qu, Zhiqiang, Yao, Weicheng, Yao, Ruyong, Liu, Xiangping, Yu, Kuai, Hartzell, Criss
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101736/ https://www.ncbi.nlm.nih.gov/pubmed/24639373 http://dx.doi.org/10.1002/cam4.232

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