Cargando…

Clinical Significance of Previously Cryptic Copy Number Alterations and Loss of Heterozygosity in Pediatric Acute Myeloid Leukemia and Myelodysplastic Syndrome Determined Using Combined Array Comparative Genomic Hybridization plus Single-Nucleotide Polymorphism Microarray Analyses

The combined array comparative genomic hybridization plus single-nucleotide polymorphism microarray (CGH+SNP microarray) platform can simultaneously detect copy number alterations (CNA) and copy-neutral loss of heterozygosity (LOH). Eighteen children with acute myeloid leukemia (AML) (n=15) or myelo...

Descripción completa

Detalles Bibliográficos
Autores principales: Koh, Kyung-Nam, Lee, Jin Ok, Seo, Eul Ju, Lee, Seong Wook, Suh, Jin Kyung, Im, Ho Joon, Seo, Jong Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101780/
https://www.ncbi.nlm.nih.gov/pubmed/25045224
http://dx.doi.org/10.3346/jkms.2014.29.7.926