Src-dependent impairment of autophagy by oxidative stress in a mouse model of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a fatal degenerative muscle disease resulting from mutations in the dystrophin gene. Increased oxidative stress and altered Ca(2+) homeostasis are hallmarks of dystrophic muscle. While impaired autophagy has recently been implicated in the disease process, the me...

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Detalles Bibliográficos
Autores principales: Pal, Rituraj, Palmieri, Michela, Loehr, James A., Li, Shumin, Abo-Zahrah, Reem, Monroe, Tanner O., Thakur, Poulami Basu, Sardiello, Marco, Rodney, George G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101811/
https://www.ncbi.nlm.nih.gov/pubmed/25028121
http://dx.doi.org/10.1038/ncomms5425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101811/
https://www.ncbi.nlm.nih.gov/pubmed/25028121
http://dx.doi.org/10.1038/ncomms5425

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