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Src-dependent impairment of autophagy by oxidative stress in a mouse model of Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a fatal degenerative muscle disease resulting from mutations in the dystrophin gene. Increased oxidative stress and altered Ca(2+) homeostasis are hallmarks of dystrophic muscle. While impaired autophagy has recently been implicated in the disease process, the me...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101811/ https://www.ncbi.nlm.nih.gov/pubmed/25028121 http://dx.doi.org/10.1038/ncomms5425 |