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Identification of novel signaling components in N,N’-Dinitrosopiperazine-mediated metastasis of nasopharyngeal Carcinoma by quantitative phosphoproteomics

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a highly invasive and metastatic cancer. N,N’-dinitrosopiperazine (DNP), a carcinogen with specificity for nasopharyngeal epithelium, facilitates NPC metastasis. However, the underlying mechanism is not known. METHODS: Quantitative phosphoproteomics, usi...

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Detalles Bibliográficos
Autores principales: Huang, Damao, Li, Yuejin, Liu, Na, Zhang, Zhenlin, Peng, Zhengke, Duan, Chaojun, Tang, Xiaowei, Tan, Gongjun, Yan, Guangrong, Tang, Faqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101831/
https://www.ncbi.nlm.nih.gov/pubmed/24708550
http://dx.doi.org/10.1186/1471-2407-14-243