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Oxidative Stress and Vitiligo: The Nrf2-ARE Signaling Connection

Hypersensitivity of epidermal melanocytes to oxidative stress is known to contribute to vitiligo pathogenesis. Molecular mechanisms that connect melanocyte redox homeostasis to the complex disease phenotype are not fully understood. Jian et al. show that vitiligo melanocytes have impaired Nrf2-ARE s...

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Detalles Bibliográficos
Autores principales: Qiu, Lei, Song, Zhiqi, Setaluri, Vijayasaradhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101905/
https://www.ncbi.nlm.nih.gov/pubmed/25029322
http://dx.doi.org/10.1038/jid.2014.241