Effect of Angiotensin II and Small GTPase Ras Signaling Pathway Inhibition on Early Renal Changes in a Murine Model of Obstructive Nephropathy

Tubulointerstitial fibrosis is a major feature of chronic kidney disease. Unilateral ureteral obstruction (UUO) in rodents leads to the development of renal tubulointerstitial fibrosis consistent with histopathological changes observed in advanced chronic kidney disease in humans. The purpose of thi...

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Detalles Bibliográficos
Autores principales: Rodríguez-Peña, Ana B., Fuentes-Calvo, Isabel, Docherty, Neil G., Arévalo, Miguel, Grande, María T., Eleno, Nélida, Pérez-Barriocanal, Fernando, López-Novoa, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101960/
https://www.ncbi.nlm.nih.gov/pubmed/25101263
http://dx.doi.org/10.1155/2014/124902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101960/
https://www.ncbi.nlm.nih.gov/pubmed/25101263
http://dx.doi.org/10.1155/2014/124902

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