Cargando…

Effect of Angiotensin II and Small GTPase Ras Signaling Pathway Inhibition on Early Renal Changes in a Murine Model of Obstructive Nephropathy

Tubulointerstitial fibrosis is a major feature of chronic kidney disease. Unilateral ureteral obstruction (UUO) in rodents leads to the development of renal tubulointerstitial fibrosis consistent with histopathological changes observed in advanced chronic kidney disease in humans. The purpose of thi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodríguez-Peña, Ana B., Fuentes-Calvo, Isabel, Docherty, Neil G., Arévalo, Miguel, Grande, María T., Eleno, Nélida, Pérez-Barriocanal, Fernando, López-Novoa, José M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101960/ https://www.ncbi.nlm.nih.gov/pubmed/25101263 http://dx.doi.org/10.1155/2014/124902

Ejemplares similares

Role of inflammation in túbulo-interstitial damage associated to obstructive nephropathy
por: Grande, María T, et al.
Publicado: (2010)

Redox-sensitive small GTPase H-Ras in murine astrocytes, an in vitro study
por: Zuchegna, Candida, et al.
Publicado: (2022)

RAS GTPases are modified by SUMOylation
por: Choi, Byeong Hyeok, et al.
Publicado: (2017)

Analysis of K-Ras Nuclear Expression in Fibroblasts and Mesangial Cells
por: Fuentes-Calvo, Isabel, et al.
Publicado: (2010)

Dissecting the Involvement of Ras GTPases in Kidney Fibrosis
por: Muñoz-Félix, José M., et al.
Publicado: (2021)

Nucleotide Binding Switches the Information Flow in Ras GTPases
por: Raimondi, Francesco, et al.
Publicado: (2011)

Evolution and Diversity of the Ras Superfamily of Small GTPases in Prokaryotes
por: Wuichet, Kristin, et al.
Publicado: (2014)

Systems level expression correlation of Ras GTPase regulators
por: Besray Unal, E., et al.
Publicado: (2018)

Emerging RAS superfamily conditions involving GTPase function
por: Shieh, Joseph T. C.
Publicado: (2019)

Subversion of Ras Small GTPases in Cutaneous Melanoma Aggressiveness
por: Brito, Cheila, et al.
Publicado: (2020)

Afadin couples RAS GTPases to the polarity rheostat Scribble
por: Goudreault, Marilyn, et al.
Publicado: (2022)

Inhibition of RAS in diabetic nephropathy
por: Yacoub, Rabi, et al.
Publicado: (2015)

The Interplay between ROS and Ras GTPases: Physiological and Pathological Implications
por: Ferro, Elisa, et al.
Publicado: (2012)

Specific Conformational States of Ras GTPase upon Effector Binding
por: Baussand, Julie, et al.
Publicado: (2012)

Ras GTPases’ interaction with effector domains: Breaking the families’ barrier
por: Patel, Manishha, et al.
Publicado: (2013)

Cysteine-based regulation of redox-sensitive Ras small GTPases
por: Messina, Samantha, et al.
Publicado: (2019)

The Ras Superfamily of Small GTPases in Non-neoplastic Cerebral Diseases
por: Qu, Liang, et al.
Publicado: (2019)

R-Ras GTPases Signaling Role in Myelin Neurodegenerative Diseases
por: Alcover-Sanchez, Berta, et al.
Publicado: (2020)

Rho Family of Ras-Like GTPases in Early-Branching Animals
por: Beljan, Silvestar, et al.
Publicado: (2020)

Angiotensin-(1-7) Attenuates Kidney Injury Due to Obstructive Nephropathy in Rats
por: Kim, Chang Seong, et al.
Publicado: (2015)

Angiotensin II, RAS Activation, and RAS Blockers in COVID-19: Unambiguous Evidence
por: Calò, Lorenzo A., et al.
Publicado: (2022)

Perspectives of RAS and RHEB GTPase Signaling Pathways in Regenerating Brain Neurons
por: Schöneborn, Hendrik, et al.
Publicado: (2018)

Membrane curvature sensing of the lipid-anchored K-Ras small GTPase
por: Liang, Hong, et al.
Publicado: (2019)

Editorial: Ras and Other GTPases in Cancer: From Basic to Applied Research
por: Cho, Kwang-jin, et al.
Publicado: (2021)

Tumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas
por: Li, Lili, et al.
Publicado: (2019)

Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors
por: Clavaín, Laura, et al.
Publicado: (2022)

L-Endoglin Overexpression Increases Renal Fibrosis after Unilateral Ureteral Obstruction
por: Oujo, Bárbara, et al.
Publicado: (2014)

cpRAS: a novel circularly permuted RAS-like GTPase domain with a highly scattered phylogenetic distribution
por: Elias, Marek, et al.
Publicado: (2008)

Specific contributions of H-Ras and N-Ras GTPases to T-lymphocyte oxidative stress and integrin-dependent retention in rheumatoid arthritis
por: Remans, PHJ, et al.
Publicado: (2005)

Is the model of signal amplification by GPCRs/GEFs activating multiple GTPases relevant to a broad spectrum of heterotrimeric and RAS superfamily GTPases?
por: Kahn, Richard A
Publicado: (2014)

Regulation of a LATS-homolog by Ras GTPases is important for the control of cell division
por: Müller-Taubenberger, Annette, et al.
Publicado: (2014)

Site–Specific Monoubiquitination Activates Ras by Impeding GTPase Activating Protein Function
por: Baker, Rachael, et al.
Publicado: (2012)

The small GTPases Ras and Rap1 bind to and control TORC2 activity
por: Khanna, Ankita, et al.
Publicado: (2016)

The Ras GTPase-Activating Protein Rasal3 Supports Survival of Naive T Cells
por: Muro, Ryunosuke, et al.
Publicado: (2015)

gRASping Depolarization: Contribution of RAS GTPases to Mitotic Polarity Clusters Resolution
por: Quadri, Roberto, et al.
Publicado: (2020)

Autophagy Stimulus-Dependent Role of the Small GTPase Ras2 in Peroxisome Degradation
por: Boutouja, Fahd, et al.
Publicado: (2020)

Ras Family of Small GTPases in CRC: New Perspectives for Overcoming Drug Resistance
por: Rio-Vilariño, Anxo, et al.
Publicado: (2021)

Divergent Mechanisms Activating RAS and Small GTPases Through Post-translational Modification
por: Osaka, Natsuki, et al.
Publicado: (2021)

The Ras small GTPase RSR1 regulates cellulase production in Trichoderma reesei
por: Li, Ni, et al.
Publicado: (2023)

Molecular Basis of Renal Adaptation in a Murine Model of Congenital Obstructive Nephropathy
por: Becknell, Brian, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_bqi8anrhod18mvov5tcgqfbi3m