ADAMTS4 and ADAMTS5 Knockout Mice Are Protected from Versican but Not Aggrecan or Brevican Proteolysis during Spinal Cord Injury

The chondroitin sulfate proteoglycans (CSPGs) aggrecan, versican, and brevican are large aggregating extracellular matrix molecules that inhibit axonal growth of the mature central nervous system (CNS). ADAMTS proteoglycanases, including ADAMTS4 and ADAMTS5, degrade CSPGs, representing potential tar...

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Detalles Bibliográficos
Autores principales: Demircan, Kadir, Topcu, Vehap, Takigawa, Tomoyuki, Akyol, Sumeyya, Yonezawa, Tomoko, Ozturk, Gulfer, Ugurcu, Veli, Hasgul, Rukiye, Yigitoglu, M. Ramazan, Akyol, Omer, McCulloch, Daniel R., Hirohata, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101972/
https://www.ncbi.nlm.nih.gov/pubmed/25101296
http://dx.doi.org/10.1155/2014/693746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101972/
https://www.ncbi.nlm.nih.gov/pubmed/25101296
http://dx.doi.org/10.1155/2014/693746

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