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Sonic hedgehog-expressing cells in the developing limb measure time by an intrinsic cell cycle clock
How time is measured is an enduring issue in developmental biology. Classical models of somitogenesis and limb development implicated intrinsic cell cycle clocks, but their existence remains controversial. Here we show that an intrinsic cell cycle clock in polarizing region cells of the chick limb b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102111/ https://www.ncbi.nlm.nih.gov/pubmed/25001275 http://dx.doi.org/10.1038/ncomms5230 |