A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel

Recent X-ray crystal structures of the two-pore domain (K2P) family of potassium channels have revealed a unique structural architecture at the point where the cytoplasmic bundle-crossing gate is found in most other tetrameric K(+) channels. However, despite the apparently open nature of the inner p...

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Detalles Bibliográficos
Autores principales: Aryal, Prafulla, Abd-Wahab, Firdaus, Bucci, Giovanna, Sansom, Mark S. P., Tucker, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102122/
https://www.ncbi.nlm.nih.gov/pubmed/25001086
http://dx.doi.org/10.1038/ncomms5377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102122/
https://www.ncbi.nlm.nih.gov/pubmed/25001086
http://dx.doi.org/10.1038/ncomms5377

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