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Caenorhabditis elegans pathways that surveil and defend mitochondria

Mitochondrial function is challenged by toxic byproducts of metabolism as well as by pathogen attack(1),(2). Caenorhabditis elegans normally responds to mitochondrial dysfunction with activation of mitochondrial repair, drug detoxification, and pathogen-response pathways(1–7). From a genome-wide RNA...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Samuel, Buck S., Breen, Peter C., Ruvkun, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102179/
https://www.ncbi.nlm.nih.gov/pubmed/24695221
http://dx.doi.org/10.1038/nature13204