Modeling Bi-modality Improves Characterization of Cell Cycle on Gene Expression in Single Cells

Advances in high-throughput, single cell gene expression are allowing interrogation of cell heterogeneity. However, there is concern that the cell cycle phase of a cell might bias characterizations of gene expression at the single-cell level. We assess the effect of cell cycle phase on gene expressi...

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Detalles Bibliográficos
Autores principales: McDavid, Andrew, Dennis, Lucas, Danaher, Patrick, Finak, Greg, Krouse, Michael, Wang, Alice, Webster, Philippa, Beechem, Joseph, Gottardo, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102402/
https://www.ncbi.nlm.nih.gov/pubmed/25032992
http://dx.doi.org/10.1371/journal.pcbi.1003696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102402/
https://www.ncbi.nlm.nih.gov/pubmed/25032992
http://dx.doi.org/10.1371/journal.pcbi.1003696

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