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Modeling Bi-modality Improves Characterization of Cell Cycle on Gene Expression in Single Cells
Advances in high-throughput, single cell gene expression are allowing interrogation of cell heterogeneity. However, there is concern that the cell cycle phase of a cell might bias characterizations of gene expression at the single-cell level. We assess the effect of cell cycle phase on gene expressi...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102402/ https://www.ncbi.nlm.nih.gov/pubmed/25032992 http://dx.doi.org/10.1371/journal.pcbi.1003696 |