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Synergy Testing of FDA-Approved Drugs Identifies Potent Drug Combinations against Trypanosoma cruzi

An estimated 8 million persons, mainly in Latin America, are infected with Trypanosoma cruzi, the etiologic agent of Chagas disease. Existing antiparasitic drugs for Chagas disease have significant toxicities and suboptimal effectiveness, hence new therapeutic strategies need to be devised to addres...

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Detalles Bibliográficos
Autores principales: Planer, Joseph D., Hulverson, Matthew A., Arif, Jennifer A., Ranade, Ranae M., Don, Robert, Buckner, Frederick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102417/
https://www.ncbi.nlm.nih.gov/pubmed/25033456
http://dx.doi.org/10.1371/journal.pntd.0002977