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Synergy Testing of FDA-Approved Drugs Identifies Potent Drug Combinations against Trypanosoma cruzi
An estimated 8 million persons, mainly in Latin America, are infected with Trypanosoma cruzi, the etiologic agent of Chagas disease. Existing antiparasitic drugs for Chagas disease have significant toxicities and suboptimal effectiveness, hence new therapeutic strategies need to be devised to addres...
Autores principales: | Planer, Joseph D., Hulverson, Matthew A., Arif, Jennifer A., Ranade, Ranae M., Don, Robert, Buckner, Frederick S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102417/ https://www.ncbi.nlm.nih.gov/pubmed/25033456 http://dx.doi.org/10.1371/journal.pntd.0002977 |
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