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Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease

The majority of the heritability of coronary artery disease (CAD) remains unexplained, despite recent successes of genome-wide association studies (GWAS) in identifying novel susceptibility loci. Integrating functional genomic data from a variety of sources with a large-scale meta-analysis of CAD GW...

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Detalles Bibliográficos
Autores principales: Mäkinen, Ville-Petteri, Civelek, Mete, Meng, Qingying, Zhang, Bin, Zhu, Jun, Levian, Candace, Huan, Tianxiao, Segrè, Ayellet V., Ghosh, Sujoy, Vivar, Juan, Nikpay, Majid, Stewart, Alexandre F. R., Nelson, Christopher P., Willenborg, Christina, Erdmann, Jeanette, Blakenberg, Stefan, O'Donnell, Christopher J., März, Winfried, Laaksonen, Reijo, Epstein, Stephen E., Kathiresan, Sekar, Shah, Svati H., Hazen, Stanley L., Reilly, Muredach P., Lusis, Aldons J., Samani, Nilesh J., Schunkert, Heribert, Quertermous, Thomas, McPherson, Ruth, Yang, Xia, Assimes, Themistocles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102418/
https://www.ncbi.nlm.nih.gov/pubmed/25033284
http://dx.doi.org/10.1371/journal.pgen.1004502