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Microsatellite Interruptions Stabilize Primate Genomes and Exist as Population-Specific Single Nucleotide Polymorphisms within Individual Human Genomes

Interruptions of microsatellite sequences impact genome evolution and can alter disease manifestation. However, human polymorphism levels at interrupted microsatellites (iMSs) are not known at a genome-wide scale, and the pathways for gaining interruptions are poorly understood. Using the 1000 Genom...

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Detalles Bibliográficos
Autores principales: Ananda, Guruprasad, Hile, Suzanne E., Breski, Amanda, Wang, Yanli, Kelkar, Yogeshwar, Makova, Kateryna D., Eckert, Kristin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102424/
https://www.ncbi.nlm.nih.gov/pubmed/25033203
http://dx.doi.org/10.1371/journal.pgen.1004498