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Structural mechanism of the dynein powerstroke
Dyneins are large microtubule motor proteins required for mitosis, intracellular transport, and ciliary and flagellar motility(1,2). They generate force through a powerstroke mechanism, which is an ATP-consuming cycle of pre- and post-powerstroke conformational changes that cause relative motion bet...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102432/ https://www.ncbi.nlm.nih.gov/pubmed/24727830 http://dx.doi.org/10.1038/ncb2939 |