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Structural mechanism of the dynein powerstroke

Dyneins are large microtubule motor proteins required for mitosis, intracellular transport, and ciliary and flagellar motility(1,2). They generate force through a powerstroke mechanism, which is an ATP-consuming cycle of pre- and post-powerstroke conformational changes that cause relative motion bet...

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Detalles Bibliográficos
Autores principales: Lin, Jianfeng, Okada, Kyoko, Raytchev, Milen, Smith, Maria C., Nicastro, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102432/
https://www.ncbi.nlm.nih.gov/pubmed/24727830
http://dx.doi.org/10.1038/ncb2939