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Comparison of Methods to Account for Relatedness in Genome-Wide Association Studies with Family-Based Data

Approaches based on linear mixed models (LMMs) have recently gained popularity for modelling population substructure and relatedness in genome-wide association studies. In the last few years, a bewildering variety of different LMM methods/software packages have been developed, but it is not always c...

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Detalles Bibliográficos
Autores principales: Eu-ahsunthornwattana, Jakris, Miller, E. Nancy, Fakiola, Michaela, Jeronimo, Selma M. B., Blackwell, Jenefer M., Cordell, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102448/
https://www.ncbi.nlm.nih.gov/pubmed/25033443
http://dx.doi.org/10.1371/journal.pgen.1004445