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Comparison of Methods to Account for Relatedness in Genome-Wide Association Studies with Family-Based Data
Approaches based on linear mixed models (LMMs) have recently gained popularity for modelling population substructure and relatedness in genome-wide association studies. In the last few years, a bewildering variety of different LMM methods/software packages have been developed, but it is not always c...
Autores principales: | Eu-ahsunthornwattana, Jakris, Miller, E. Nancy, Fakiola, Michaela, Jeronimo, Selma M. B., Blackwell, Jenefer M., Cordell, Heather J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102448/ https://www.ncbi.nlm.nih.gov/pubmed/25033443 http://dx.doi.org/10.1371/journal.pgen.1004445 |
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