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Protection from Hemolytic Uremic Syndrome by Eyedrop Vaccination with Modified Enterohemorrhagic E. coli Outer Membrane Vesicles

We investigated whether eyedrop vaccination using modified outer membrane vesicles (mOMVs) is effective for protecting against hemolytic uremic syndrome (HUS) caused by enterohemorrhagic E. coli (EHEC) O157:H7 infection. Modified OMVs and waaJ-mOMVs were prepared from cultures of MsbB- and Shiga tox...

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Detalles Bibliográficos
Autores principales: Choi, Kyoung Sub, Kim, Sang-Hyun, Kim, Eun-Do, Lee, Sang-Ho, Han, Soo Jung, Yoon, Sangchul, Chang, Kyu-Tae, Seo, Kyoung Yul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102476/
https://www.ncbi.nlm.nih.gov/pubmed/25032703
http://dx.doi.org/10.1371/journal.pone.0100229