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Oxygen Transport and Stem Cell Aggregation in Stirred-Suspension Bioreactor Cultures

Stirred-suspension bioreactors are a promising modality for large-scale culture of 3D aggregates of pluripotent stem cells and their progeny. Yet, cells within these clusters experience limitations in the transfer of factors and particularly O(2) which is characterized by low solubility in aqueous m...

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Detalles Bibliográficos
Autores principales: Wu, Jincheng, Rostami, Mahboubeh Rahmati, Cadavid Olaya, Diana P., Tzanakakis, Emmanuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102498/
https://www.ncbi.nlm.nih.gov/pubmed/25032842
http://dx.doi.org/10.1371/journal.pone.0102486