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Oxygen Transport and Stem Cell Aggregation in Stirred-Suspension Bioreactor Cultures
Stirred-suspension bioreactors are a promising modality for large-scale culture of 3D aggregates of pluripotent stem cells and their progeny. Yet, cells within these clusters experience limitations in the transfer of factors and particularly O(2) which is characterized by low solubility in aqueous m...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102498/ https://www.ncbi.nlm.nih.gov/pubmed/25032842 http://dx.doi.org/10.1371/journal.pone.0102486 |