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Effects of Treatment with Suppressive Combination Antiretroviral Drug Therapy and the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid; (SAHA) on SIV-Infected Chinese Rhesus Macaques

OBJECTIVES: Viral reservoirs–persistent residual virus despite combination antiretroviral therapy (cART)–remain an obstacle to cure of HIV-1 infection. Difficulty studying reservoirs in patients underscores the need for animal models that mimics HIV infected humans on cART. We studied SIV-infected C...

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Detalles Bibliográficos
Autores principales: Ling, Binhua, Piatak, Michael, Rogers, Linda, Johnson, Ann-Marie, Russell-Lodrigue, Kasi, Hazuda, Daria J., Lifson, Jeffrey D., Veazey, Ronald S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102539/
https://www.ncbi.nlm.nih.gov/pubmed/25033210
http://dx.doi.org/10.1371/journal.pone.0102795