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Decay-Accelerating Factor 1 Deficiency Exacerbates Leptospiral-Induced Murine Chronic Nephritis and Renal Fibrosis

Leptospirosis is a global zoonosis caused by pathogenic Leptospira, which can colonize the proximal renal tubules and persist for long periods in the kidneys of infected hosts. Here, we characterized the infection of C57BL/6J wild-type and Daf1(−/−) mice, which have an enhanced host response, with a...

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Detalles Bibliográficos
Autores principales: Ferrer, María F., Scharrig, Emilia, Alberdi, Lucrecia, Cedola, Maia, Pretre, Gabriela, Drut, Ricardo, Song, Wen-Chao, Gomez, Ricardo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102560/
https://www.ncbi.nlm.nih.gov/pubmed/25032961
http://dx.doi.org/10.1371/journal.pone.0102860