Cargando…

Peptidoglycan Recognition Proteins Kill Bacteria by Inducing Oxidative, Thiol, and Metal Stress

Mammalian Peptidoglycan Recognition Proteins (PGRPs) are a family of evolutionary conserved bactericidal innate immunity proteins, but the mechanism through which they kill bacteria is unclear. We previously proposed that PGRPs are bactericidal due to induction of reactive oxygen species (ROS), a me...

Descripción completa

Detalles Bibliográficos
Autores principales: Kashyap, Des Raj, Rompca, Annemarie, Gaballa, Ahmed, Helmann, John D., Chan, Jefferson, Chang, Christopher J., Hozo, Iztok, Gupta, Dipika, Dziarski, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102600/
https://www.ncbi.nlm.nih.gov/pubmed/25032698
http://dx.doi.org/10.1371/journal.ppat.1004280