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Peptidoglycan Recognition Proteins Kill Bacteria by Inducing Oxidative, Thiol, and Metal Stress
Mammalian Peptidoglycan Recognition Proteins (PGRPs) are a family of evolutionary conserved bactericidal innate immunity proteins, but the mechanism through which they kill bacteria is unclear. We previously proposed that PGRPs are bactericidal due to induction of reactive oxygen species (ROS), a me...
Autores principales: | Kashyap, Des Raj, Rompca, Annemarie, Gaballa, Ahmed, Helmann, John D., Chan, Jefferson, Chang, Christopher J., Hozo, Iztok, Gupta, Dipika, Dziarski, Roman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102600/ https://www.ncbi.nlm.nih.gov/pubmed/25032698 http://dx.doi.org/10.1371/journal.ppat.1004280 |
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