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Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs

BACKGROUND: Gene expression genetic studies in human tissues and cells identify cis- and trans-acting expression quantitative trait loci (eQTLs). These eQTLs provide insights into regulatory mechanisms underlying disease risk. However, few studies systematically characterized eQTL results across cel...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoling, Gierman, Hinco J, Levy, Daniel, Plump, Andrew, Dobrin, Radu, Goring, Harald HH, Curran, Joanne E, Johnson, Matthew P, Blangero, John, Kim, Stuart K, O’Donnell, Christopher J, Emilsson, Valur, Johnson, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102726/
https://www.ncbi.nlm.nih.gov/pubmed/24973796
http://dx.doi.org/10.1186/1471-2164-15-532