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Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling

In mammals, Wnt/β-catenin signaling features prominently in stem cells and cancers, but how and for what purposes have been matters of much debate. In this review, we summarize our current knowledge of Wnt/β-catenin signaling and its downstream transcriptional regulators in normal and malignant stem...

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Detalles Bibliográficos
Autores principales: Lien, Wen-Hui, Fuchs, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102759/
https://www.ncbi.nlm.nih.gov/pubmed/25030692
http://dx.doi.org/10.1101/gad.244772.114