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Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling
In mammals, Wnt/β-catenin signaling features prominently in stem cells and cancers, but how and for what purposes have been matters of much debate. In this review, we summarize our current knowledge of Wnt/β-catenin signaling and its downstream transcriptional regulators in normal and malignant stem...
Autores principales: | Lien, Wen-Hui, Fuchs, Elaine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102759/ https://www.ncbi.nlm.nih.gov/pubmed/25030692 http://dx.doi.org/10.1101/gad.244772.114 |
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