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Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling

Protein quality control is essential in all organisms and regulated by the proteostasis network (PN) and cell stress response pathways that maintain a functional proteome to promote cellular health. In this review, we describe how metazoans employ multiple modes of cell-nonautonomous signaling acros...

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Detalles Bibliográficos
Autores principales: van Oosten-Hawle, Patricija, Morimoto, Richard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102760/
https://www.ncbi.nlm.nih.gov/pubmed/25030693
http://dx.doi.org/10.1101/gad.241125.114